Description

Carbamic Acid, n-[trans-4-[2-[(Methylsulfonyl)Oxy]Ethyl]Cyclohexyl]-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and functional groups. This compound matters for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and metabolic pathways. Pharmaceutical R&D and manufacturing organizations need this precisely defined intermediate to ensure the efficacy, purity, and regulatory compliance of their final drug products.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of novel therapeutic agents, especially in central nervous system (CNS) and metabolic disorder research.
• Protease Inhibitor Development: Serves as a precursor in the design and production of protease inhibitors, a major class of antiviral and anticancer drugs.
• Peptidomimetic Chemistry: Used to introduce the trans-cyclohexyl and sulfonate ester motifs into peptidomimetic structures to enhance metabolic stability and bioavailability.
• Chemical Biology Research: Employed as a tool compound or labeling agent in biochemical assays to study enzyme function and signal transduction pathways.
• Process Chemistry & Scale-Up: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for process optimization and commercial-scale API manufacturing under GMP guidelines.

Basic Information

Product Name	Carbamic Acid, n-[trans-4-[2-[(Methylsulfonyl)Oxy]Ethyl]Cyclohexyl]-, 1,1-Dimethylethyl Ester
CAS No.	917342-28-0
Molecular Formula	C16H31NO5S
Molecular Weight	349.49 g/mol
Synonyms	tert-Butyl N-[trans-4-[2-(methylsulfonyloxy)ethyl]cyclohexyl]carbamate; trans-4-(2-((Methylsulfonyl)oxy)ethyl)cyclohexanamine 1,1-dimethylethyl ester; Boc-trans-4-(2-(methylsulfonyloxy)ethyl)cyclohexylamine; (trans-4-(2-(Methanesulfonyloxy)ethyl)cyclohexyl)carbamic acid tert-butyl ester; tert-Butyl (trans-4-(2-(methylsulfonyloxy)ethyl)cyclohexyl)carbamate; BOC-4-(2-Mesyloxyethyl)cyclohexylamine (trans); 917342-28-0; Carbamic acid, N-[trans-4-[2-[(methylsulfonyl)oxy]ethyl]cyclohexyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, n-[trans-4-[2-[(Methylsulfonyl)Oxy]Ethyl]Cyclohexyl]-, 1,1-Dimethylethyl Ester adheres to stringent quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and identification via NMR and IR spectroscopy. Certificates of Analysis (COA) detailing all specifications and test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (trans-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.