Description

6-(Methoxycarbonyl)-2-(4-Methylphenyl)Imidazo[1,2-A]Pyridine-3-Acetic Acid is a high-purity, advanced pharmaceutical intermediate with the CAS number 917252-80-3. This compound is a critical building block in the synthesis of complex heterocyclic molecules, valued for its precise chemical structure and reactivity. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

This specialized intermediate serves as a key precursor in several high-value chemical synthesis pathways. Its primary applications include:

• Pharmaceutical Research & Development: As a core scaffold for synthesizing potential drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Active Pharmaceutical Ingredient (API) Synthesis: A crucial building block in the multi-step synthesis of complex APIs, especially those containing the imidazopyridine moiety.
• Fine Chemical Production: Used in the manufacture of high-value specialty chemicals for agrochemical and material science applications.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis projects and process development.
• Academic Research: Employed in university and institutional labs for studying heterocyclic chemistry and reaction mechanisms.

Basic Information

Product Name	6-(Methoxycarbonyl)-2-(4-Methylphenyl)Imidazo[1,2-A]Pyridine-3-Acetic Acid
CAS No.	917252-80-3
Molecular Formula	C₁₉H₁₆N₂O₄
Molecular Weight	336.34 g/mol
Synonyms	2-(4-Methylphenyl)-6-(methoxycarbonyl)imidazo[1,2-a]pyridine-3-acetic acid; 6-Carbomethoxy-2-(p-tolyl)imidazo[1,2-a]pyridine-3-acetic Acid; Imidazo[1,2-a]pyridine-3-acetic acid, 6-(methoxycarbonyl)-2-(4-methylphenyl)-; Methyl 3-(carboxymethyl)-2-(4-methylphenyl)imidazo[1,2-a]pyridine-6-carboxylate; 917252-80-3; 6-Methoxycarbonyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetic acid
EINECS	Contact for details

Quality Control

Our production of 6-(Methoxycarbonyl)-2-(4-Methylphenyl)Imidazo[1,2-A]Pyridine-3-Acetic Acid adheres to stringent quality management protocols. Every batch is subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality systems are designed to support cGMP compliance for pharmaceutical applications, ensuring reliability for critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep the container tightly sealed when not in use to prevent any potential contamination or moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.