Description

3-(2-Aminoethyl)-1H-Pyrrolo[2,3-B]Pyridin-5-Ol is a high-purity, heterocyclic organic compound featuring a fused pyrrolopyridine core with an aminoethyl side chain, making it a valuable and versatile building block in advanced chemical synthesis. This compound is critical for research and development in the pharmaceutical sector, particularly in the design of novel small-molecule therapeutics targeting complex biological pathways. It is primarily sought after by medicinal chemists and process development scientists working in drug discovery for oncology, neurology, and other therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a privileged scaffold in structure-activity relationship (SAR) studies and lead optimization programs.
• Bioconjugation & Probe Development: The aminoethyl side chain facilitates conjugation to fluorescent dyes, biotin, or other molecules for creating biochemical probes.
• Chemical Biology: Employed in the synthesis of tool compounds for investigating enzyme function and cellular signaling pathways.
• Process Chemistry: Utilized in the scale-up and route development for the commercial manufacturing of active pharmaceutical ingredients (APIs).
• Academic Research: A valuable reagent for universities and research institutes exploring new heterocyclic chemistry and bioorganic synthesis.

Basic Information

Product Name	3-(2-Aminoethyl)-1H-Pyrrolo[2,3-B]Pyridin-5-Ol
CAS No.	916895-89-1
Molecular Formula	C9H11N3O
Molecular Weight	177.20 g/mol
Synonyms	5-Hydroxy-3-(2-aminoethyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridin-5-ol, 3-(2-aminoethyl)-; 3-(2-Aminoethyl)-5-hydroxy-1H-pyrrolo[2,3-b]pyridine; 5-Hydroxy-3-(2-aminoethyl)-7-azaindole; 3-(2-Aminoethyl)-5-hydroxy-7-azaindole; AZD-1283 Intermediate; Pyrrolopyridine derivative
EINECS	Contact for details

Quality Control

Every batch of 3-(2-Aminoethyl)-1H-Pyrrolo[2,3-B]Pyridin-5-Ol is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency that meet the exacting standards of pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.