Description

Ethyl 3-(6-Bromopyridin-3-Yl)-3-Oxopropanoate is a high-purity brominated pyridine derivative and a versatile β-keto ester building block. This compound is critical for the synthesis of complex heterocyclic molecules, offering a reactive handle for further functionalization. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the pyridine core for bioactivity.
• Chemical Research: Serves as a fundamental building block in organic synthesis for constructing complex heterocycles like quinolines, naphthyridines, and fused ring systems.
• Material Science Precursor: Potential use in the development of organic ligands for catalysis or functional materials.
• Contract Manufacturing (CMO): Supplied to custom synthesis organizations for scale-up and production under cGMP guidelines for clinical trial materials.

Basic Information

Product Name	Ethyl 3-(6-Bromopyridin-3-Yl)-3-Oxopropanoate
CAS No.	916791-37-2
Molecular Formula	C10H10BrNO3
Molecular Weight	272.10 g/mol
Synonyms	Ethyl 3-(6-bromopyridin-3-yl)-3-oxopropanoate; 3-(6-Bromo-3-pyridinyl)-3-oxopropanoic Acid Ethyl Ester; Ethyl (6-Bromonicotinoyl)acetate; 6-Bromonicotinoylacetic Acid Ethyl Ester; Ethyl 6-Bromonicotinoylacetate; 3-Oxo-3-(6-bromopyridin-3-yl)propanoic acid ethyl ester; Acetic acid, 2-(6-bromo-3-pyridinyl)-2-oxo-, ethyl ester
EINECS	Contact for details

Quality Control

Every batch of Ethyl 3-(6-Bromopyridin-3-Yl)-3-Oxopropanoate is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) confirming identity, purity (typically ≥95% by HPLC), and impurity profile is available with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.