Description

Pentafluorophenyl (4-Methyl-6,7-Dihydro-4H-Thieno[3,2-C]Pyran-4-Yl)Acetate is a high-value, specialized fluorinated heterocyclic building block designed for advanced synthetic chemistry. This compound is critical for researchers and process chemists developing novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique pentafluorophenyl ester group offers superior reactivity in coupling reactions. It is primarily utilized in pharmaceutical R&D, agrochemical synthesis, and advanced material science for creating complex molecular architectures with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the thienopyran scaffold for bioactivity.
• Peptide & Protein Modification: The reactive pentafluorophenyl ester moiety is effective for efficient amide bond formation and bioconjugation strategies.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers and organic electronic materials.
• Chemical Biology Probe Development: Employed to create fluorescent tags, affinity labels, and other molecular probes for studying biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity fluorinated intermediates.

Basic Information

Product Name	Pentafluorophenyl (4-Methyl-6,7-Dihydro-4H-Thieno[3,2-C]Pyran-4-Yl)Acetate
CAS No.	916766-89-7
Molecular Formula	C18H13F5O3S
Molecular Weight	404.35 g/mol
Synonyms	4-Methyl-6,7-dihydro-4H-thieno[3,2-c]pyran-4-yl acetate pentafluorophenyl ester; 2,3,4,5,6-Pentafluorophenyl (4-methyl-4,6,7-trihydrothieno[3,2-c]pyran-4-yl)acetate; (4-Methyl-6,7-dihydro-4H-thieno[3,2-c]pyran-4-yl)acetic acid pentafluorophenyl ester; Pentafluorophenyl 2-(4-methyl-6,7-dihydro-4H-thieno[3,2-c]pyran-4-yl)acetate; CAS 916766-89-7; Thienopyran pentafluorophenyl ester; Fluorinated thienopyran derivative.
EINECS	Contact for details

Quality Control

Our Pentafluorophenyl (4-Methyl-6,7-Dihydro-4H-Thieno[3,2-C]Pyran-4-Yl)Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.