Description

(S)-Ethyl 3-Methyl-2-((R)-5-(Perfluorophenyl)-3-Styryl-1,2,4-Oxadiazol-4(5H)-Yl)Butanoate is a high-purity, chiral fluorinated oxadiazole derivative, a critical advanced intermediate for pharmaceutical and agrochemical research. Its complex stereochemistry and unique perfluorophenyl-styryl-oxadiazole scaffold make it invaluable for developing novel bioactive compounds with enhanced metabolic stability and target specificity. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry, asymmetric synthesis, and the development of new crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and anti-infective research programs.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorinated moiety for improved lipophilicity and environmental persistence.
• Asymmetric Catalysis & Ligand Synthesis: Serves as a precursor for chiral ligands or catalysts in stereoselective synthesis due to its defined (S) and (R) stereocenters.
• Material Science Precursor: Potential use in synthesizing specialty polymers or liquid crystals where the fluorinated aromatic system can impart unique electronic and surface properties.
• Chemical Biology Probe Development: Utilized in creating fluorescent or photoaffinity labels for studying biological pathways and protein-ligand interactions.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of complex target molecules.

Basic Information

Product Name	(S)-Ethyl 3-Methyl-2-((R)-5-(Perfluorophenyl)-3-Styryl-1,2,4-Oxadiazol-4(5H)-Yl)Butanoate
CAS No.	916676-23-8
Molecular Formula	C24H21F5N2O3
Molecular Weight	480.43 g/mol
Synonyms	Ethyl (2S)-3-methyl-2-[(4R)-5-(pentafluorophenyl)-3-[(E)-2-phenylethenyl]-1,2,4-oxadiazol-4-yl]butanoate; (S)-Ethyl 3-methyl-2-((R)-5-(perfluorophenyl)-3-styryl-1,2,4-oxadiazol-4(5H)-yl)butyrate; 916676-23-8; Fluorinated Styryl Oxadiazole Ester; Chiral Perfluorophenyl Oxadiazole Derivative; (S,R)-Oxadiazole Butanoate Ester
EINECS	Contact for details

Quality Control

Every batch of (S)-Ethyl 3-Methyl-2-((R)-5-(Perfluorophenyl)-3-Styryl-1,2,4-Oxadiazol-4(5H)-Yl)Butanoate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for demanding research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.