Description

Methyl 5-Bromo-1-Methyl-1H-Pyrazolo[3,4-B]Pyridine-3-Carboxylate is a high-purity, functionalized pyrazolopyridine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for medicinal chemistry research and development, enabling the creation of novel pharmacologically active molecules. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers for the synthesis of potential drug candidates, particularly in kinase inhibitor and other targeted therapy programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Kinase Inhibitor Development: Serves as a core scaffold for research into protein kinase inhibitors due to the pyrazolopyridine structure's affinity for ATP-binding sites.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to improve potency and selectivity.
• Agrochemical Synthesis: Employed in the research and development of new active ingredients for crop protection products.
• Chemical Biology Probes: Utilized to create molecular probes for studying biological processes and target validation.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up production under cGMP conditions for clinical trial materials.

Basic Information

Product Name	Methyl 5-Bromo-1-Methyl-1H-Pyrazolo[3,4-B]Pyridine-3-Carboxylate
CAS No.	916326-80-2
Molecular Formula	C10H8BrN3O2
Molecular Weight	282.09 g/mol
Synonyms	5-Bromo-1-methyl-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid methyl ester; Methyl 5-bromo-1-methyl-1H-pyrazolo[3,4-b]pyridine-3-carboxylate; 1-Methyl-5-bromo-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid methyl ester; 916326-80-2; 5-Bromo-1-methyl-pyrazolo[3,4-b]pyridine-3-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 5-Bromo-1-Methyl-1H-Pyrazolo[3,4-B]Pyridine-3-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant regulatory frameworks, and specifications can be aligned with client requirements for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.