Description

(R)-3-Azido-2-(4-Bromobenzyl)Propanoic Acid is a chiral, non-natural amino acid derivative featuring both an azido functional group and a brominated aromatic side chain. This compound is a high-value building block in organic synthesis, particularly for the preparation of complex molecules via click chemistry and cross-coupling reactions. It is primarily utilized by pharmaceutical researchers and agrochemical developers for creating novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates, including protease inhibitors and other biologically active molecules.
• Click Chemistry Substrate: The azide group enables efficient, high-yielding Huisgen 1,3-dipolar cycloaddition reactions with alkynes to form triazole linkages, useful in bioconjugation and materials science.
• Suzuki-Miyaura Cross-Coupling: The 4-bromobenzyl moiety serves as an excellent handle for palladium-catalyzed coupling with various boronic acids to diversify molecular structure.
• Peptidomimetic Research: Used to incorporate non-standard amino acid units into peptide backbones to modulate stability, activity, and bioavailability.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides and fungicides with chiral centers.
• Ligand and Catalyst Development: Employed in the creation of chiral ligands for asymmetric catalysis.
• Chemical Biology Probes: Useful for labeling and studying biological systems due to its bio-orthogonal reactivity.

Basic Information

Product Name	(R)-3-Azido-2-(4-Bromobenzyl)Propanoic Acid
CAS No.	916323-00-7
Molecular Formula	C₁₀H₁₀BrN₃O₂
Molecular Weight	284.11 g/mol
Synonyms	(R)-3-Azido-2-(4-bromobenzyl)propanoic acid; (R)-2-(4-Bromobenzyl)-3-azidopropanoic Acid; (R)-α-(4-Bromobenzyl)-β-azidopropionic Acid; (2R)-2-[(4-Bromophenyl)methyl]-3-azidopropanoic Acid; (R)-3-Azido-2-(p-bromobenzyl)propionic Acid; Azido-Br-Phe-OH (R-isomer); (R)-AIDA(Br)
EINECS	Contact for details

Quality Control

Our (R)-3-Azido-2-(4-Bromobenzyl)Propanoic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC to ensure high enantiomeric purity and identity confirmation via NMR and mass spectrometry. Certificates of Analysis (COA) with detailed specifications are provided to guarantee consistent quality and traceability for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Enantiomeric Excess (Chiral HPLC)	≥98.0%
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.