Description

(R)-3-Azido-2-(2-Chlorobenzyl)Propanoic Acid is a high-purity chiral building block of significant interest in advanced organic synthesis. This compound is valued for its unique molecular architecture, featuring an azido group and a chlorobenzyl moiety, which makes it a versatile precursor for the development of complex bioactive molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutic agents.
• Peptidomimetic Synthesis: Serves as a constrained amino acid analog for constructing peptide-like molecules with enhanced metabolic stability and bioavailability.
• Click Chemistry Substrate: The azido functional group enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation and polymer chemistry applications.
• Agrochemical Research: Used as a building block in the synthesis of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Potential monomer or cross-linker for the synthesis of specialized polymers with tailored properties.
• Chemical Biology Probes: Useful for labeling and studying biological systems due to its reactive azide handle.

Basic Information

Product Name	(R)-3-Azido-2-(2-Chlorobenzyl)Propanoic Acid
CAS No.	916322-99-1
Molecular Formula	C₁₀H₁₀ClN₃O₂
Molecular Weight	239.66 g/mol
Synonyms	(R)-3-Azido-2-[(2-chlorophenyl)methyl]propanoic acid; (R)-2-(2-Chlorobenzyl)-3-azidopropanoic acid; (R)-α-(2-Chlorobenzyl)-β-azidopropionic Acid; (2R)-2-[(2-Chlorophenyl)methyl]-3-azidopropanoic acid; (R)-3-Azido-2-(2-chlorobenzyl)propionic acid; Azido-CBP; (R)-Azido-CBPA
EINECS	Contact for details

Quality Control

Our (R)-3-Azido-2-(2-Chlorobenzyl)Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profiles is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature, the container should be opaque or kept in dark conditions. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.