Description

(R)-3-Azido-2-(3-Chlorobenzyl)Propanoic Acid is a chiral, non-natural amino acid derivative featuring both an azido functional group and a chlorinated aromatic side chain. This compound is a crucial chiral building block in the synthesis of complex pharmaceutical intermediates and bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for applications in medicinal chemistry and asymmetric synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates, especially protease inhibitors and other enzyme-targeted therapies.
• Peptidomimetics Research: Used to incorporate azido and chlorobenzyl motifs into peptide backbones, enabling "click chemistry" modifications and structure-activity relationship (SAR) studies.
• Chemical Biology Probes: The azide group allows for bioorthogonal conjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC), useful for labeling and tracking biomolecules.
• Asymmetric Synthesis: Serves as a starting material or intermediate in the preparation of enantiomerically pure compounds for catalysis and material science.
• Agrochemical Research: Potential intermediate in the development of novel, chiral active ingredients for crop protection.

Basic Information

Product Name	(R)-3-Azido-2-(3-Chlorobenzyl)Propanoic Acid
CAS No.	916322-98-0
Molecular Formula	C10H10ClN3O2
Molecular Weight	239.66 g/mol
Synonyms	(R)-3-Azido-2-(3-chlorobenzyl)propanoic acid; (R)-2-(3-Chlorobenzyl)-3-azidopropanoic acid; (3R)-2-[(3-Chlorophenyl)methyl]-3-azidopropanoic acid; (R)-α-(3-Chlorobenzyl)-β-azidopropionic Acid; Azido-(3-chlorobenzyl)-propionic acid (R-enantiomer); (R)-3-Azido-2-(3-chlorobenzyl)propionic acid; (R)-3-Azido-2-(3-Cl-Bn)propanoic acid
EINECS	Contact for details

Quality Control

Our (R)-3-Azido-2-(3-Chlorobenzyl)Propanoic Acid is manufactured under strict quality control protocols to ensure high chemical and enantiomeric purity suitable for research and development. Each batch is analyzed using advanced chromatographic and spectroscopic techniques. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided to guarantee consistency and support your regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label/Certificate of Analysis. This material is easily oxidized; for long-term storage, consider under an inert atmosphere. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.