Description

(R)-3-Azido-2-(4-Methoxybenzyl)Propanoic Acid CAS NO 916322-94-6 is a chiral, non-natural amino acid derivative featuring an azido functional group, making it a versatile building block for advanced organic synthesis. Its primary value lies in its role as a key intermediate in the preparation of complex molecules, particularly through click chemistry and peptide coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing novel therapeutics, diagnostics, and chemical probes.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially peptidomimetics and protease inhibitors.
• Click Chemistry Reagent: The azido group enables efficient, high-yield Huisgen 1,3-dipolar cycloaddition reactions with alkynes to form triazole linkages, useful in bioconjugation and material science.
• Peptide Modification: Used to introduce functional handles or labels into peptide chains for drug discovery and biochemical research.
• Ligand and Probe Development: Serves as a precursor for creating specialized ligands, imaging agents, and molecular probes in medicinal chemistry.
• Asymmetric Synthesis: The chiral center provides a scaffold for constructing enantiomerically pure compounds in asymmetric catalysis and synthesis.
• Academic and R&D: A valuable tool for chemical research in universities and corporate R&D laboratories exploring new synthetic methodologies.

Basic Information

Product Name	(R)-3-Azido-2-(4-Methoxybenzyl)Propanoic Acid
CAS No.	916322-94-6
Molecular Formula	C11H13N3O3
Molecular Weight	235.24 g/mol
Synonyms	(R)-3-Azido-2-(4-Methoxybenzyl)propanoic acid; (R)-2-(4-Methoxybenzyl)-3-azidopropanoic acid; (R)-3-Azido-2-[(4-methoxyphenyl)methyl]propanoic acid; (R)-α-(4-Methoxybenzyl)-β-azidopropionic Acid; (R)-3-Azido-2-PMB-propanoic Acid; (R)-Azd-Pab-OH; (R)-Azd-PMB-OH; (2R)-3-Azido-2-[(4-methoxyphenyl)methyl]propanoic acid
EINECS	Contact for details

Quality Control

Our (R)-3-Azido-2-(4-Methoxybenzyl)Propanoic Acid is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients in regulated development pathways.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated place, away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.