Description

(S)-3-Azido-2-(3-Chlorobenzyl)Propanamide is a chiral, azide-functionalized organic building block of significant interest in advanced synthetic chemistry. Its core value lies in its dual functionality, where the azide group enables efficient click chemistry reactions, and the chiral center provides stereochemical control, making it a critical intermediate for constructing complex molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptidomimetics, and specialized polymers.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel therapeutic agents, particularly in medicinal chemistry programs.
• Peptidomimetic Synthesis: Used to introduce azide handles and chiral elements into peptide backbones for creating stable, bioactive analogs.
• Click Chemistry Substrate: The azide group participates in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation and polymer functionalization.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Incorporated into specialty polymers and dendrimers to impart specific functional properties.
• Academic & Industrial R&D: A valuable tool for chemical biology studies and exploring new synthetic methodologies in organic chemistry.

Basic Information

Product Name	(S)-3-Azido-2-(3-Chlorobenzyl)Propanamide
CAS No.	916322-88-8
Molecular Formula	C10H11ClN4O
Molecular Weight	238.67 g/mol
Synonyms	(S)-3-Azido-2-[(3-chlorophenyl)methyl]propanamide; (S)-2-(3-Chlorobenzyl)-3-azidopropanamide; L-3-Azido-2-(3-chlorobenzyl)propionamide; Propanamide, 3-azido-2-[(3-chlorophenyl)methyl]-, (2S)-; (2S)-3-Azido-2-[(3-chlorophenyl)methyl]propanamide; Azide-functionalized chiral building block
EINECS	Contact for details

Quality Control

Our (S)-3-Azido-2-(3-Chlorobenzyl)Propanamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and potential for oxidation, it is recommended to store the material under an inert atmosphere for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.