Description

(S)-3-Azido-2-(4-Chlorobenzyl)Propanamide is a chiral, non-natural amino acid derivative featuring an azido functional group, making it a valuable synthetic intermediate. This compound is of significant interest for its role in click chemistry and as a building block in medicinal chemistry and peptide research. It is primarily utilized by pharmaceutical R&D teams, agrochemical scientists, and academic researchers focused on developing novel bioactive molecules and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates, protease inhibitors, and other biologically active molecules.
• Peptide Chemistry: Used to incorporate azido-modified amino acids into peptides for subsequent bioconjugation via click chemistry (e.g., CuAAC with alkynes).
• Agrochemical Research: Serves as a building block in the development of novel pesticides and herbicides with specific chiral configurations.
• Chemical Biology Probes: Enables the creation of activity-based probes and affinity labels for studying enzyme function and protein interactions.
• Material Science: A precursor for functionalized polymers and smart materials where the azide group facilitates cross-linking or surface modification.
• Academic & Contract Research: Employed in universities and CROs for methodological development in asymmetric synthesis and bioorthogonal chemistry.

Basic Information

Product Name	(S)-3-Azido-2-(4-Chlorobenzyl)Propanamide
CAS No.	916322-87-7
Molecular Formula	C₁₀H₁₁ClN₄O
Molecular Weight	238.67 g/mol
Synonyms	(S)-3-Azido-2-(4-chlorobenzyl)propanamide; (2S)-3-Azido-2-[(4-chlorophenyl)methyl]propanamide; L-3-Azido-2-(4-chlorobenzyl)propionamide; (S)-3-Azido-2-(p-chlorobenzyl)propionamide; Azido-Cpg-OH; N/A
EINECS	Contact for details

Quality Control

Our (S)-3-Azido-2-(4-Chlorobenzyl)Propanamide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its sensitivity to oxidation. Keep away from heat, sparks, and open flames. For long-term storage, consider storing desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.