Description

(R)-3-Azido-2-Benzylpropanoic Acid is a chiral, non-natural amino acid derivative featuring an azido functional group. This compound is a crucial chiral building block in organic synthesis, enabling the stereoselective introduction of nitrogen-containing functionalities. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors, antiviral agents, and other small molecule therapeutics.
• Peptidomimetics & Conjugation: Serves as a versatile handle for "click chemistry" via the azide group, facilitating the construction of complex peptide analogs and bioconjugates.
• Asymmetric Synthesis: Used as a starting material or auxiliary in catalytic asymmetric reactions to construct stereogenic centers with high enantiomeric purity.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes and labeled compounds for target identification and mechanistic studies.
• Ligand & Catalyst Development: Acts as a precursor for chiral ligands and organocatalysts used in enantioselective transformations.
• Material Science: Potential monomer for creating functionalized polymers with specific chemical handles for further modification.

Basic Information

Product Name	(R)-3-Azido-2-Benzylpropanoic Acid
CAS No.	916322-65-1
Molecular Formula	C10H11N3O2
Molecular Weight	205.21 g/mol
Synonyms	(R)-3-Azido-2-benzylpropanoic acid; (R)-2-Benzyl-3-azidopropanoic acid; (R)-α-Benzyl-β-azidopropionic Acid; (R)-3-Azido-2-(phenylmethyl)propanoic acid; (2R)-3-Azido-2-benzylpropanoic acid; (R)-Homoazidophenylalanine; Azido-D-hPhe; Azido-(R)-hPhe
EINECS	Contact for details

Quality Control

Our (R)-3-Azido-2-Benzylpropanoic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, to ensure high chemical and optical purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its sensitivity to oxidation and moisture. Keep away from heat, sparks, and open flame. For long-term storage, consider storing at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.