Description

(S)-3-Azido-2-Benzylpropanamide is a chiral, azide-functionalized organic building block of significant interest in synthetic chemistry. Its value lies in its role as a versatile intermediate for the synthesis of more complex molecules, particularly through click chemistry reactions like the copper-catalyzed azide-alkyne cycloaddition (CuAAC). This compound is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, proteomics, and the development of novel bioconjugates and drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially those containing nitrogen heterocycles.
• Click Chemistry Reagent: Utilized in CuAAC reactions to efficiently introduce amide-linked triazole functionalities into peptides, proteins, polymers, and other biomolecules for labeling and conjugation.
• Medicinal Chemistry Probe: Used to create targeted molecular probes and libraries for studying biological pathways and protein-protein interactions.
• Peptidomimetic Synthesis: Serves as a constrained, non-natural amino acid analog in the design of peptide-based therapeutics with enhanced stability and bioavailability.
• Material Science Research: Employed in the surface functionalization of nanomaterials and the synthesis of specialty polymers with tailored properties.

Basic Information

Product Name	(S)-3-Azido-2-Benzylpropanamide
CAS No.	916322-64-0
Molecular Formula	C₁₀H₁₂N₄O
Molecular Weight	204.23 g/mol
Synonyms	(S)-2-Benzyl-3-azidopropanamide; (S)-3-Azido-2-benzylpropionamide; L-3-Azido-2-benzylpropanamide; (2S)-3-Azido-2-benzylpropanamide; 2-Benzyl-3-azidopropanamide; Azido-Phe-NH2 (common abbreviation); (S)-α-Benzyl-β-azidopropionamide
EINECS	Contact for details

Quality Control

Our (S)-3-Azido-2-Benzylpropanamide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.