Description

C-(2-Trifluoromethyl-Pyridin-4-Yl)-Methylamine is a high-value, fluorinated pyridine derivative building block essential for advanced organic synthesis. This compound matters for its role in introducing the trifluoromethylpyridyl moiety, a key pharmacophore known to enhance metabolic stability, lipophilicity, and binding affinity in active molecules. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients, particularly in medicinal chemistry for drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in oncology, CNS, and antiviral research.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the trifluoromethylpyridine group improves efficacy and environmental profile.
• Ligand & Catalyst Development: Serves as a precursor for specialized ligands in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and advanced polymers.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up production under cGMP conditions.
• Bioconjugation & Probe Chemistry: Useful for modifying biomolecules or creating fluorescent probes and diagnostic agents in life sciences.

Basic Information

Product Name	C-(2-Trifluoromethyl-Pyridin-4-Yl)-Methylamine
CAS No.	916304-20-6
Molecular Formula	C8H7F3N2
Molecular Weight	188.15 g/mol
Synonyms	4-(Aminomethyl)-2-(trifluoromethyl)pyridine; 2-(Trifluoromethyl)-4-pyridinemethanamine; (2-Trifluoromethylpyridin-4-yl)methanamine; 4-(Aminomethyl)-α,α,α-trifluoro-2-picoline; 2-Trifluoromethyl-4-pyridylmethylamine; α,α,α-Trifluoro-2-picoline-4-methanamine; 4-(Aminomethyl)-2-(trifluoromethyl)pyridine; 916304-20-6
EINECS	Contact for details

Quality Control

Our C-(2-Trifluoromethyl-Pyridin-4-Yl)-Methylamine is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring material for GLP, GMP, and ISO-compliant research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.