Description

C-(6-Trifluoromethyl-Pyridin-2-Yl)-Methylamine is a high-purity, specialized organic building block featuring a pyridine core substituted with a trifluoromethyl group and an aminomethyl side chain. This compound is valued for its role as a critical intermediate in the synthesis of advanced pharmaceutical agents and agrochemicals, where its unique fluorine-containing scaffold imparts desirable metabolic stability and bioavailability. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis for asymmetric synthesis.
• Material Science Research: Employed in the synthesis of advanced organic materials, such as liquid crystals or organic semiconductors, where its electronic properties are beneficial.
• Chemical Biology Probes: Utilized as a building block for designing molecular probes and tags used in biochemical assays and diagnostic research.

Basic Information

Product Name	C-(6-Trifluoromethyl-Pyridin-2-Yl)-Methylamine
CAS No.	916304-19-3
Molecular Formula	C8H7F3N2
Molecular Weight	188.15 g/mol
Synonyms	2-(Aminomethyl)-6-(trifluoromethyl)pyridine; (6-(Trifluoromethyl)pyridin-2-yl)methanamine; 2-(Trifluoromethyl)-6-pyridinemethanamine; 6-(Trifluoromethyl)-2-pyridinemethylamine; α-(6-Trifluoromethyl-2-pyridyl)methylamine; 2-Pyridinemethanamine, 6-(trifluoromethyl)-; C-(6-Trifluoromethyl-Pyridin-2-Yl)-Methylamine
EINECS	Contact for details

Quality Control

Our C-(6-Trifluoromethyl-Pyridin-2-Yl)-Methylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high standards, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.