Description

1H-Pyrazolo[3,4-B]Pyridine-1-Carboxylic Acid, 5-Bromo-3-(Bromomethyl)-, 1,1-Dimethylethyl Ester is a high-value brominated pyrazolopyridine derivative, serving as a critical pharmaceutical intermediate and building block in advanced organic synthesis. Its molecular structure, featuring reactive bromomethyl and ester functionalities, makes it indispensable for constructing complex heterocyclic scaffolds. This compound is primarily sought by R&D laboratories and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Building block for developing new crop protection compounds and herbicides.
• Chemical Biology: Used in the design and synthesis of molecular probes and enzyme inhibitors.
• Material Science: Intermediate for creating advanced organic electronic materials and ligands for catalysis.
• Custom Synthesis: Serves as a versatile starting material for contract research organizations (CROs) and CDMOs.
• Academic Research: Utilized in universities and institutes for methodological development in heterocyclic chemistry.

Basic Information

Product Name	1H-Pyrazolo[3,4-B]Pyridine-1-Carboxylic Acid, 5-Bromo-3-(Bromomethyl)-, 1,1-Dimethylethyl Ester
CAS No.	916258-26-9
Molecular Formula	C13H14Br2N2O2
Molecular Weight	390.07 g/mol
Synonyms	5-Bromo-3-(bromomethyl)-1H-pyrazolo[3,4-b]pyridine-1-carboxylic acid tert-butyl ester; tert-Butyl 5-bromo-3-(bromomethyl)-1H-pyrazolo[3,4-b]pyridine-1-carboxylate; 5-Bromo-3-(bromomethyl)-1-(tert-butoxycarbonyl)-1H-pyrazolo[3,4-b]pyridine; 1H-Pyrazolo[3,4-b]pyridine-1-carboxylic acid, 5-bromo-3-(bromomethyl)-, 1,1-dimethylethyl ester; 916258-26-9; tert-Butyl 5-bromo-3-(bromomethyl)pyrazolo[3,4-b]pyridine-1-carboxylate
EINECS	Contact for details

Quality Control

Our 1H-Pyrazolo[3,4-B]Pyridine-1-Carboxylic Acid, 5-Bromo-3-(Bromomethyl)-, 1,1-Dimethylethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality management system is designed to meet the stringent requirements of our global pharmaceutical and fine chemical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.