Description

(2-(Trifluoromethyl)Pyridin-4-Yl)Methanamine Dihydrochloride is a high-purity, organofluorine building block essential for modern pharmaceutical and agrochemical research. Its core value lies in the unique trifluoromethylpyridine scaffold, which is prized for enhancing the metabolic stability, lipophilicity, and bioavailability of lead compounds. This intermediate is critically needed by R&D chemists and process development scientists in the life sciences sector for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of small molecule drugs, particularly in oncology, CNS disorders, and anti-infective therapies.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and insecticides, where the CF3 group improves efficacy and environmental profile.
• Chemical Biology & Proteomics: Serves as a versatile building block for creating molecular probes and activity-based protein profiling (ABPP) reagents.
• Material Science: Potential precursor for specialty polymers and liquid crystals that require fluorinated aromatic components for specific electronic or surface properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and scale-up projects under cGMP or ISO quality systems.

Basic Information

Item	Detail
Product Name	(2-(Trifluoromethyl)Pyridin-4-Yl)Methanamine Dihydrochloride
CAS No.	916211-41-1
Molecular Formula	C7H8Cl2F3N2
Molecular Weight	251.06 g/mol
Synonyms	4-(Aminomethyl)-2-(trifluoromethyl)pyridine dihydrochloride; 2-(Trifluoromethyl)-4-pyridinemethanamine dihydrochloride; 4-(Aminomethyl)-α,α,α-trifluoro-2-picoline dihydrochloride; (2-Trifluoromethyl-4-pyridyl)methylamine dihydrochloride; 2-Trifluoromethyl-4-aminomethylpyridine dihydrochloride; 4-(Aminomethyl)-2-(trifluoromethyl)pyridine hydrochloride (1:2)
EINECS	Contact for details

Quality Control

Our (2-(Trifluoromethyl)Pyridin-4-Yl)Methanamine Dihydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, supporting development work under ISO and cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.