Description

tert-Butyl ((6-(Trifluoromethyl)Pyridin-2-Yl)Methyl)Carbamate is a high-value, protected amine building block featuring a pyridine core substituted with a trifluoromethyl group. This compound is critical for medicinal chemistry and agrochemical research, where its structure provides unique electronic and steric properties to modulate the bioactivity of target molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the development of small-molecule drugs, particularly for kinase inhibitors and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the stability imparted by the trifluoromethyl group.
• Peptide Mimetics & PROTACs: Serves as a versatile building block for constructing peptide-like structures and Proteolysis Targeting Chimeras (PROTACs).
• Ligand & Catalyst Development: Employed in the creation of novel ligands for metal catalysis and organocatalysts due to its pyridine nitrogen and sterically hindered carbamate.
• Material Science Research: Investigated as a monomer or functional additive for specialty polymers with tailored surface properties.
• Chemical Biology Probes: Utilized to synthesize molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	tert-Butyl ((6-(Trifluoromethyl)Pyridin-2-Yl)Methyl)Carbamate
CAS No.	916210-32-7
Molecular Formula	C12H15F3N2O2
Molecular Weight	276.26 g/mol
Synonyms	Boc-6-(Trifluoromethyl)picolylamine; N-Boc-2-(Aminomethyl)-6-(trifluoromethyl)pyridine; tert-Butyl N-[[6-(trifluoromethyl)-2-pyridyl]methyl]carbamate; 2-(((tert-Butoxycarbonyl)amino)methyl)-6-(trifluoromethyl)pyridine; (6-(Trifluoromethyl)pyridin-2-yl)methanaminium, N-Boc protected; Boc-Amine-Pyridine-CF3; BOC-6-TFM-Pic-NH2
EINECS	Contact for details

Quality Control

Our tert-Butyl ((6-(Trifluoromethyl)Pyridin-2-Yl)Methyl)Carbamate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided to support your GMP and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.