Description

tert-Butyl n-[(2-Chloropyridin-4-Yl)Methyl]Carbamate CAS NO 916210-27-0 is a high-purity, protected amine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for their synthetic routes.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the chloropyridine moiety.
• Chemical Research & Development: A versatile reagent for constructing complex heterocyclic compounds and exploring new synthetic methodologies in academic and industrial labs.
• Peptidomimetics & Bioactive Molecule Construction: The protected carbamate group makes it suitable for introducing amine functionalities in peptide-like structures and other bioactive molecules.
• Material Science Precursor: Potential intermediate in the synthesis of specialized ligands for catalysts or functional organic materials.

Basic Information

Product Name	tert-Butyl n-[(2-Chloropyridin-4-Yl)Methyl]Carbamate
CAS No.	916210-27-0
Molecular Formula	C11H15ClN2O2
Molecular Weight	242.70 g/mol
Synonyms	Boc-4-(Aminomethyl)-2-chloropyridine; 2-Chloro-4-((((tert-butoxy)carbonyl)amino)methyl)pyridine; tert-Butyl (2-chloropyridin-4-yl)methylcarbamate; N-Boc-2-chloro-4-aminomethylpyridine; (2-Chloro-4-pyridylmethyl)carbamic acid tert-butyl ester; 4-((tert-Butoxycarbonylamino)methyl)-2-chloropyridine; 2-Chloro-4-((Boc-amino)methyl)pyridine; Boc-2-chloro-4-(aminomethyl)pyridine
EINECS	Contact for details

Quality Control

Our tert-Butyl n-[(2-Chloropyridin-4-Yl)Methyl]Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.