Description

4-Bromo-2-Chloro-3-Iodopyridine is a highly functionalized halogenated pyridine derivative, serving as a critical multi-purpose building block in advanced organic synthesis. Its unique substitution pattern makes it an indispensable intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and antiviral therapies.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Development: Serves as a foundational scaffold for creating novel ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient pyridine core.
• Cross-Coupling Reactions: An excellent substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) to introduce the pyridine moiety into more complex systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.

Basic Information

Product Name	4-Bromo-2-Chloro-3-Iodopyridine
CAS No.	916203-52-6
Molecular Formula	C5H2BrClIN
Molecular Weight	318.34 g/mol
Synonyms	2-Chloro-4-bromo-3-iodopyridine; 3-Iodo-4-bromo-2-chloropyridine; Pyridine, 4-bromo-2-chloro-3-iodo-; 4-Bromo-2-chloro-3-iodo-pyridine; 916203-52-6; BCPY; 4-Br-2-Cl-3-I-pyridine
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Chloro-3-Iodopyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.