Description

4-Methyl-3,4-Dihydro-2H-Pyrido[3,2-B][1,4]Oxazine-7-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by pharmaceutical R&D organizations, contract research and manufacturing services (CRAMS) providers, and fine chemical suppliers engaged in the development of next-generation drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and other specialized therapeutic areas.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new bioactive molecules.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a core scaffold or a crucial fragment in multi-step synthetic routes for novel APIs.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and cGMP production of clinical trial materials and commercial drugs.
• Chemical Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	4-Methyl-3,4-Dihydro-2H-Pyrido[3,2-B][1,4]Oxazine-7-Carboxylic Acid
CAS No.	915707-58-3
Molecular Formula	C10H12N2O3
Molecular Weight	208.22 g/mol
Synonyms	7-Carboxy-4-methyl-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine; 4-Methyl-2H,3H,4H-pyrido[3,2-b][1,4]oxazine-7-carboxylic acid; 915707-58-3; Pyridooxazine-7-carboxylic acid derivative; CAS 915707-58-3
EINECS	Contact for details

Quality Control

Our 4-Methyl-3,4-Dihydro-2H-Pyrido[3,2-B][1,4]Oxazine-7-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical development. Certificates of Analysis (COA) with detailed chromatographic data are available for every shipment. We support development with custom purity grades and specifications aligned with cGMP and ICH Q7 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.