Description

2-(Chloromethyl)-5-Fluoropyridine Hydrochloride is a high-purity, versatile pharmaceutical intermediate and organic building block. This compound is valued for its bifunctional reactivity, featuring both a chloromethyl group and a fluoropyridine core, which enables its use in complex synthetic pathways. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, leveraging the fluoropyridine moiety for enhanced biological activity.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of functionalized polymers and advanced organic materials with specific electronic or binding properties.
• Chemical Biology Probes: Utilized to synthesize molecular probes and tags for studying biological processes and target engagement.

Basic Information

Product Name	2-(Chloromethyl)-5-Fluoropyridine Hydrochloride
CAS No.	915409-01-7
Molecular Formula	C6H6Cl2FN
Molecular Weight	182.02 g/mol
Synonyms	5-Fluoro-2-(chloromethyl)pyridine hydrochloride; 2-Chloromethyl-5-fluoropyridine HCl; (5-Fluoro-2-pyridinyl)methyl chloride hydrochloride; 5-Fluoro-2-pyridinemethyl chloride hydrochloride; 2-Pyridinemethanol, 5-fluoro-, chloride, hydrochloride
EINECS	Contact for details

Quality Control

Our 2-(Chloromethyl)-5-Fluoropyridine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.