Description

(R)-tert-Butyl 1-([1,2,4]Triazolo[4,3-A]Pyridin-3-Yl)Ethylcarbamate is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders and other therapeutic areas. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in process development and scale-up of novel drug candidates.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and commercial synthesis of novel drug candidates.
• API Synthesis: Used in the construction of complex molecules for potential treatments of neurological and psychiatric conditions.
• Process Chemistry: Serves as a critical starting material or intermediate in route scouting, optimization, and kilogram-scale production.
• Asymmetric Synthesis: Exploits its chiral center for the stereoselective construction of biologically active compounds.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.

Basic Information

Product Name	(R)-tert-Butyl 1-([1,2,4]Triazolo[4,3-A]Pyridin-3-Yl)Ethylcarbamate
CAS No.	915375-35-8
Molecular Formula	C13H18N4O2
Molecular Weight	262.31 g/mol
Synonyms	(R)-1-((tert-Butoxycarbonyl)amino)ethyl[1,2,4]triazolo[4,3-a]pyridine; (R)-tert-Butyl (1-([1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl)carbamate; (R)-Boc-1-([1,2,4]triazolo[4,3-a]pyridin-3-yl)ethylamine; (R)-N-Boc-1-(triazolopyridin-3-yl)ethylamine; tert-Butyl (R)-(1-([1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl)carbamate; (R)-1-(1,2,4-Triazolo[4,3-a]pyridin-3-yl)ethyl carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our (R)-tert-Butyl 1-([1,2,4]Triazolo[4,3-A]Pyridin-3-Yl)Ethylcarbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for pharmaceutical development. Certificates of Analysis (COA) detailing identity, purity (typically >98% by HPLC), chiral excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.