Description

(S)-tert-Butyl 1-([1,2,4]Triazolo[4,3-A]Pyridin-3-Yl)Ethylcarbamate is a high-purity, advanced pharmaceutical intermediate characterized by its chiral center and fused heterocyclic structure. This compound is of significant value in medicinal chemistry for the synthesis of novel active pharmaceutical ingredients (APIs) targeting central nervous system and other therapeutic areas. It is primarily required by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of small-molecule drugs.

Application

• Key Intermediate in API Synthesis: Serves as a critical building block in the multi-step synthesis of complex drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new pharmacophores.
• Preclinical Development: Employed in the production of batches for pharmacological and toxicological evaluation.
• Chiral Synthesis: The (S)-enantiomer provides stereochemical control for creating enantiomerically pure final compounds.
• Process Chemistry Scale-Up: Supplied for route scouting and optimization from milligram to kilogram scale.
• Reference Standard: Used as an analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	(S)-tert-Butyl 1-([1,2,4]Triazolo[4,3-A]Pyridin-3-Yl)Ethylcarbamate
CAS No.	915375-33-6
Molecular Formula	C13H18N4O2
Molecular Weight	262.31 g/mol
Synonyms	(S)-1-([1,2,4]Triazolo[4,3-a]pyridin-3-yl)ethyl carbamic acid tert-butyl ester; tert-Butyl N-[(1S)-1-([1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl]carbamate; (S)-tert-Butyl (1-(1,2,4-triazolo[4,3-a]pyridin-3-yl)ethyl)carbamate; Boc-(S)-1-(1,2,4-triazolo[4,3-a]pyridin-3-yl)ethylamine; (S)-1-(1,2,4-Triazolo[4,3-a]pyridin-3-yl)ethylamine, N-Boc protected; 915375-33-6; (S)-Boc-Amino-[1,2,4]triazolo[4,3-a]pyridine derivative
EINECS	Contact for details

Quality Control

Our (S)-tert-Butyl 1-([1,2,4]Triazolo[4,3-A]Pyridin-3-Yl)Ethylcarbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric purity, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP manufacturing. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere or in a controlled humidity environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.