Description

(R)-tert-Butyl 1-Oxo-1-(2-(Pyridin-2-Yl)Hydrazinyl)Propan-2-Ylcarbamate is a high-purity chiral building block and advanced pharmaceutical intermediate of significant importance in modern synthetic chemistry. Its value lies in its role as a key precursor for the development of novel, optically active active pharmaceutical ingredients (APIs) and complex organic molecules. This compound is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the synthesis of targeted therapeutics, particularly in areas requiring specific stereochemistry.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Asymmetric Synthesis: Used as a building block in stereoselective reactions to construct complex molecular architectures with high enantiomeric purity.
• Peptidomimetic Research: Serves as a constrained amino acid derivative in the design and synthesis of peptide analogs and mimetics for drug discovery.
• Ligand and Catalyst Development: Employed in the preparation of novel pyridine-hydrazine based ligands for catalytic systems and metal complexes.
• Agrochemical Intermediates: Potential use in the synthesis of advanced, chiral active ingredients for crop protection products.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	(R)-tert-Butyl 1-Oxo-1-(2-(Pyridin-2-Yl)Hydrazinyl)Propan-2-Ylcarbamate
CAS No.	915375-27-8
Molecular Formula	C13H20N4O3
Molecular Weight	280.33 g/mol
Synonyms	(R)-tert-Butyl (1-oxo-1-((2-(pyridin-2-yl)hydrazinyl))propan-2-yl)carbamate; (R)-2-((tert-Butoxycarbonyl)amino)-N'-(pyridin-2-yl)propanehydrazide; (R)-Boc-Ala-NH-NH-Py; (R)-N-Boc-alanine pyridin-2-ylhydrazide; (R)-N-(tert-Butoxycarbonyl)alanine 2-pyridylhydrazide; 915375-27-8; (R)-N-Boc-Ala-NNH-Py
EINECS	Contact for details

Quality Control

Our (R)-tert-Butyl 1-Oxo-1-(2-(Pyridin-2-Yl)Hydrazinyl)Propan-2-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC to ensure high enantiomeric excess (e.e.) and identity confirmation by spectroscopic methods. We provide detailed Certificates of Analysis (COA) with each shipment, documenting purity, assay, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent degradation. Keep container tightly sealed in a desiccated environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.