Description

4-(1-Azetidine Carbonyl)-Benzoic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its unique azetidine and benzoate ester structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing novel drug candidates. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing new therapeutic agents, particularly in areas requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting neurological and metabolic disorders.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new drug candidates with improved efficacy and safety profiles.
• Protease Inhibitor Development: The azetidine carbonyl moiety makes it a valuable precursor for designing protease and kinase inhibitors.
• Custom Synthesis & Contract Manufacturing: Sourced by CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.
• Chemical Biology Probes: Utilized in the development of chemical probes for studying biological pathways and target validation.

Basic Information

Product Name	4-(1-Azetidine Carbonyl)-Benzoic Acid Methyl Ester
CAS No.	915199-14-3
Molecular Formula	C12H13NO3
Molecular Weight	219.24 g/mol
Synonyms	Methyl 4-(azetidine-1-carbonyl)benzoate; Benzoic acid, 4-(1-azetidinylcarbonyl)-, methyl ester; 4-(Azetidine-1-carbonyl)benzoic acid methyl ester; Methyl 4-(1-azetidinecarbonyl)benzoate; Azetidine-1-carboxylic acid, 4-(methoxycarbonyl)phenyl ester; 915199-14-3
EINECS	Contact for details

Quality Control

Our 4-(1-Azetidine Carbonyl)-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the exacting standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.