Description

3-[5-(Trifluoromethyl)Pyridin-3-Yl]Propanoic Acid is a high-purity organic building block featuring a pyridine core substituted with a trifluoromethyl group and a propanoic acid side chain. This compound is valued for its role as a versatile intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is essential for medicinal chemists and process development scientists working on novel active ingredients, where its unique trifluoromethylated pyridine scaffold can impart desirable metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in catalysis and material science applications.
• Chemical Biology Probes: Employed in the design of molecular probes and tags for studying biological processes and target engagement.
• Advanced Material Research: Utilized as a monomer or functionalization agent in the development of specialty polymers and functional materials.

Basic Information

Product Name	3-[5-(Trifluoromethyl)Pyridin-3-Yl]Propanoic Acid
CAS No.	915030-12-5
Molecular Formula	C9H6F3NO2
Molecular Weight	217.14 g/mol
Synonyms	3-[5-(Trifluoromethyl)-3-pyridinyl]propanoic acid; 3-(5-(Trifluoromethyl)pyridin-3-yl)propanoic acid; 3-(5-Trifluoromethylpyridin-3-yl)propionic Acid; 5-(Trifluoromethyl)pyridine-3-propanoic acid; 3-Pyridinepropanoic acid, 5-(trifluoromethyl)-; 915030-12-5
EINECS	Contact for details

Quality Control

Our 3-[5-(Trifluoromethyl)Pyridin-3-Yl]Propanoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.