Description

5-Amino-2-Bromo-6-Iodopyridine is a high-purity, multi-halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring distinct bromo and iodo substituents on an amino-pyridine core, makes it an exceptionally versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for targeted therapies and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine scaffold.
• Material Science: Serves as a building block for creating specialized ligands, organic semiconductors, and photoactive compounds.
• Cross-Coupling Reactions: The bromo and iodo groups are excellent substrates for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig amination, enabling rapid diversification.
• Chemical Biology & Medicinal Chemistry: Employed in fragment-based drug discovery and as a probe for studying biological interactions due to its modifiable functional groups.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses producing bespoke compounds for client R&D programs.

Basic Information

Product Name	5-Amino-2-Bromo-6-Iodopyridine
CAS No.	915006-52-9
Molecular Formula	C5H4BrIN2
Molecular Weight	298.91 g/mol
Synonyms	2-Bromo-6-iodopyridin-5-amine; 5-Amino-2-bromo-6-iodopyridine; 2-Bromo-5-amino-6-iodopyridine; 6-Iodo-5-amino-2-bromopyridine; Pyridine, 5-amino-2-bromo-6-iodo-; 915006-52-9; AI3-31862
EINECS	Contact for details

Quality Control

Every batch of 5-Amino-2-Bromo-6-Iodopyridine is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We provide Certificates of Analysis (COA) that detail purity, identity, and impurity profiles, ensuring traceability and compliance with your project specifications. Our standard quality commitment aligns with cGMP principles for advanced intermediates, and we support regulatory filings with necessary documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from prolonged exposure and to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.