Description

Methyl 6-Ethynylpyridine-2-Carboxylate is a high-value, multifunctional pyridine derivative featuring both an ethynyl and an ester functional group. This unique structure makes it a versatile and critical building block for advanced organic synthesis, particularly in the development of complex molecular architectures. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for constructing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules requiring a functionalized pyridine core.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the ethynyl group enables further chemical modifications.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, metal-organic frameworks (MOFs), and polymers due to its rigid, conjugated structure.
• Click Chemistry Substrate: The terminal alkyne group makes it an ideal candidate for Huisgen cycloaddition (click chemistry) reactions to rapidly build complex molecules.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and enzyme activity.

Basic Information

Product Name	Methyl 6-Ethynylpyridine-2-Carboxylate
CAS No.	914950-66-6
Molecular Formula	C9H7NO2
Molecular Weight	161.16 g/mol
Synonyms	Methyl 6-ethynylpicolinate; 2-Pyridinecarboxylic acid, 6-ethynyl-, methyl ester; 6-Ethynylpicolinic acid methyl ester; Methyl 6-ethynyl-2-pyridinecarboxylate; 6-Ethynylpyridine-2-carboxylic acid methyl ester; Methyl 2-(ethynyl)pyridine-6-carboxylate
EINECS	Contact for details

Quality Control

Every batch of Methyl 6-Ethynylpyridine-2-Carboxylate is produced and tested under a strict quality management system to ensure batch-to-batch consistency and high purity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Residue on Ignition	< 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.