Description

5-Oxo-1-Pyridin-3-Ylpyrrolidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a defined heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory research. It is essential for medicinal chemistry research and development, serving pharmaceutical manufacturers and contract research organizations (CROs) focused on innovative drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug candidates, especially those targeting neurological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• API Development: Serves as a precursor in the development of Active Pharmaceutical Ingredients (APIs) with potential analgesic or anti-inflammatory properties.
• Biochemical Reagent: Employed in biochemical assays and as a reference standard for analytical method development and validation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Item	Details
Product Name	5-Oxo-1-Pyridin-3-Ylpyrrolidine-3-Carboxylic Acid
CAS No.	914637-52-8
Molecular Formula	C10H10N2O3
Molecular Weight	206.20 g/mol
Synonyms	1-(3-Pyridinyl)-3-pyrrolidinecarboxylic acid, 5-oxo-; 5-Oxo-1-(pyridin-3-yl)pyrrolidine-3-carboxylic acid; 3-Pyridinepropanamide, α,γ-dioxo-N-3-pyridinyl-; 914637-52-8; 5-Oxo-1-(3-pyridyl)pyrrolidine-3-carboxylic acid; 1-(3-Pyridinyl)-5-oxopyrrolidine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Oxo-1-Pyridin-3-Ylpyrrolidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure compliance with research and development grade specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.