Description

5-Oxo-1-Pyridin-4-Ylpyrrolidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrrolidone scaffold fused with a pyridine moiety. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within the fields of central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Protease Inhibitor Development: Its structural features make it relevant for research into inhibitors targeting specific enzymes.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and drug discovery methodologies.

Basic Information

Item	Detail
Product Name	5-Oxo-1-Pyridin-4-Ylpyrrolidine-3-Carboxylic Acid
CAS No.	914637-50-6
Molecular Formula	C11H10N2O3
Molecular Weight	218.21 g/mol
Synonyms	1-(4-Pyridinyl)-3-pyrrolidinecarboxylic acid, 5-oxo-; 5-Oxo-1-(4-pyridinyl)-3-pyrrolidinecarboxylic acid; 3-Carboxy-1-(4-pyridyl)-2-pyrrolidinone; 1-(Pyridin-4-yl)-5-oxopyrrolidine-3-carboxylic acid; 4-Pyridin-1,5-dioxo-pyrrolidine-3-carboxylic acid; (RS)-5-Oxo-1-(pyridin-4-yl)pyrrolidine-3-carboxylic acid; 914637-50-6
EINECS	Contact for details

Quality Control

Our 5-Oxo-1-Pyridin-4-Ylpyrrolidine-3-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request. We support compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.