Description

4-Pyridinecarboxylic Acid, 2-(1-Piperazinyl)- is a heterocyclic organic compound featuring a pyridine core substituted with a carboxylic acid and a piperazine moiety. This unique molecular architecture makes it a valuable pharmaceutical intermediate and a versatile building block for medicinal chemistry research and fine chemical synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Building Block: Used for structure-activity relationship (SAR) studies and library synthesis due to its modifiable carboxylic acid and piperazine functional groups.
• Ligand Synthesis: Serves as a starting material for creating chelating agents or ligands in catalytic and coordination chemistry.
• Bioconjugation Reagent: The carboxylic acid group allows for coupling to biomolecules, useful in probe and diagnostic agent development.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialty chemicals and advanced materials.
• Research & Development: Essential for academic and industrial research exploring new heterocyclic compounds with potential biological activity.

Basic Information

Product Name	4-Pyridinecarboxylic Acid, 2-(1-Piperazinyl)-
CAS No.	914637-26-6
Molecular Formula	C10H13N3O2
Molecular Weight	207.23 g/mol
Synonyms	2-(Piperazin-1-yl)isonicotinic Acid; 2-(1-Piperazinyl)isonicotinic Acid; 2-Piperazin-1-ylpyridine-4-carboxylic Acid; 4-Pyridinecarboxylic acid, 2-(1-piperazinyl)-; Isonicotinic acid, 2-(1-piperazinyl)-; 2-Piperazinylisonicotinic Acid
EINECS	Contact for details

Quality Control

Our 4-Pyridinecarboxylic Acid, 2-(1-Piperazinyl)- is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and other relevant spectroscopic methods. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.