Description

4-[6-(Trifluoromethyl)Pyridin-2-Yl]Morpholine is a high-value, fluorinated heterocyclic building block that combines a pyridine core with a morpholine substituent. This compound is critical for introducing specific steric and electronic properties into target molecules, making it a sought-after intermediate in advanced organic synthesis. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the design and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers in the development of specialty polymers and advanced materials.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4-[6-(Trifluoromethyl)Pyridin-2-Yl]Morpholine
CAS No.	914636-87-6
Molecular Formula	C10H11F3N2O
Molecular Weight	232.20 g/mol
Synonyms	2-(4-Morpholinyl)-6-(trifluoromethyl)pyridine; 6-(Trifluoromethyl)-2-morpholinopyridine; 4-(6-(Trifluoromethyl)pyridin-2-yl)morpholine; 2-Morpholino-6-(trifluoromethyl)pyridine; N-(6-(Trifluoromethyl)pyridin-2-yl)morpholine; 914636-87-6; 4-(6-Trifluoromethyl-2-pyridinyl)morpholine
EINECS	Contact for details

Quality Control

Our 4-[6-(Trifluoromethyl)Pyridin-2-Yl]Morpholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and scale-up applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.