Description

4-Chloro-5-Fluoro-1-Methyl-6-Oxo-1,6-Dihydro-Pyridine-3-Carboxylic Acid Ethyl Ester is a high-value, multi-functional heterocyclic building block essential for modern synthetic chemistry. This compound is specifically engineered to serve as a critical intermediate in the development of complex active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antibacterial agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Fine Chemical Building Block: Employed in academic and industrial research for constructing complex heterocyclic compounds and exploring new chemical spaces.
• Material Science Research: Potential precursor for the development of specialty chemicals, ligands for catalysis, and functional organic materials.

Basic Information

Product Name	4-Chloro-5-Fluoro-1-Methyl-6-Oxo-1,6-Dihydro-Pyridine-3-Carboxylic Acid Ethyl Ester
CAS No.	914358-80-8
Molecular Formula	C9H9ClFNO3
Molecular Weight	233.62 g/mol
Synonyms	Ethyl 4-Chloro-5-fluoro-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate; 4-Chloro-5-fluoro-1-methyl-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxylic acid ethyl ester; 1,6-Dihydro-4-chloro-5-fluoro-1-methyl-6-oxo-3-pyridinecarboxylic acid ethyl ester; 914358-80-8; 4-Chloro-5-fluoro-1-methyl-6-oxo-1,6-dihydro-3-pyridinecarboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Fluoro-1-Methyl-6-Oxo-1,6-Dihydro-Pyridine-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.