Description

3-(2,4-Difluorophenyl)Pyridine is a high-purity fluorinated pyridine derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique molecular structure, which incorporates both a pyridine ring and a difluorophenyl group, making it a versatile building block for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis for asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as components for OLEDs (Organic Light-Emitting Diodes) and semiconductors.
• Fluorine Chemistry Studies: A valuable substrate for investigating new fluorination reactions and studying structure-activity relationships (SAR) in medicinal chemistry.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up processes.

Basic Information

Product Name	3-(2,4-Difluorophenyl)Pyridine
CAS No.	914349-57-8
Molecular Formula	C11H7F2N
Molecular Weight	191.18 g/mol
Synonyms	2,4-Difluoro-3-pyridinylbenzene; 3-Pyridinyl-2,4-difluorobenzene; (2,4-Difluorophenyl)pyridine; 3-(2,4-Difluorophenyl)pyridine; Pyridine, 3-(2,4-difluorophenyl)-; 914349-57-8
EINECS	Contact for details

Quality Control

Our 3-(2,4-Difluorophenyl)Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC, GC, NMR, and mass spectrometry results. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is supplied with each batch to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.