Description

(1-Pyridin-2-Ylmethylpiperidin-4-Yl)Methanol is a sophisticated nitrogen-containing heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key chiral intermediate for constructing complex pharmacologically active molecules, offering a versatile scaffold for medicinal chemistry research and development. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting the central nervous system.

Application

• Pharmaceutical Intermediate: A critical chiral building block in the synthesis of novel drug candidates, especially for neurological and psychiatric disorders.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and advanced materials.
• Academic Research: A valuable compound for methodological development in organic synthesis and asymmetric catalysis at universities and research institutes.

Basic Information

Product Name	(1-Pyridin-2-Ylmethylpiperidin-4-Yl)Methanol
CAS No.	914349-21-6
Molecular Formula	C12H18N2O
Molecular Weight	206.29 g/mol
Synonyms	4-Piperidinemethanol, 1-[(2-pyridinyl)methyl]-; 1-[(Pyridin-2-yl)methyl]piperidin-4-ylmethanol; (1-((Pyridin-2-yl)methyl)piperidin-4-yl)methanol; 1-(Pyridin-2-ylmethyl)piperidin-4-ylmethanol; 4-(Hydroxymethyl)-1-(2-pyridylmethyl)piperidine; (1-Pyridin-2-ylmethyl-piperidin-4-yl)-methanol; 1-(2-Pyridylmethyl)-4-piperidinemethanol
EINECS	Contact for details

Quality Control

Our (1-Pyridin-2-Ylmethylpiperidin-4-Yl)Methanol is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, NMR for structural confirmation, and Karl Fischer titration for moisture content. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.