Description

2-Chloro-4-(4-Methoxyphenyl)Pyridine is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and functional materials, where its specific substitution pattern enables precise molecular design. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor research and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its pyridine core for bioactivity.
• Ligand Synthesis: Serves as a building block for creating complex ligands used in catalysis and material science.
• Functional Material Development: Incorporated into the design of organic electronic materials, such as those for OLEDs, due to its electron-deficient aromatic system.
• Chemical Biology Probes: Utilized in the construction of molecular probes for studying biological pathways and protein functions.
• Custom Synthesis & Scale-Up: Supplied for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects from milligram to kilogram scale.

Basic Information

Product Name	2-Chloro-4-(4-Methoxyphenyl)Pyridine
CAS No.	914303-35-8
Molecular Formula	C12H10ClNO
Molecular Weight	219.67 g/mol
Synonyms	2-Chloro-4-(4-methoxyphenyl)pyridine; 4-(4-Methoxyphenyl)-2-chloropyridine; 2-Chloro-4-(p-methoxyphenyl)pyridine; 914303-35-8; 2-Chloro-4-(4'-methoxyphenyl)pyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-(4-Methoxyphenyl)Pyridine is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. Our standard grade typically meets a purity specification of ≥97% (by HPLC), with detailed impurity profiling available. Certificates of Analysis (COA) documenting identity, purity, and related substances are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.