Description

tert-Butyl 2-Cyano-2-(5-Nitropyridin-2-Yl)Acetate is a high-value, multi-functional chemical intermediate featuring a nitropyridine core and a cyanoacetate ester group. This compound matters for its role as a versatile building block in the synthesis of complex heterocyclic molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting kinase inhibition or containing complex pyridine-based heterocycles.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its reactive nitropyridine moiety.
• Chemical Research: Serves as a versatile precursor in organic synthesis for creating libraries of compounds for high-throughput screening.
• Material Science: Potential intermediate in the development of specialty polymers or organic electronic materials due to its conjugated system.
• Dye and Pigment Industry: Can be utilized in the synthesis of specialized nitro- and cyano-substituted colorants.

Basic Information

Product Name	tert-Butyl 2-Cyano-2-(5-Nitropyridin-2-Yl)Acetate
CAS No.	914223-27-1
Molecular Formula	C12H13N3O4
Molecular Weight	263.25 g/mol
Synonyms	2-(5-Nitro-2-pyridinyl)-2-cyanoacetic acid 1,1-dimethylethyl ester; tert-Butyl (5-nitropyridin-2-yl)(cyano)acetate; 2-Cyano-2-(5-nitropyridin-2-yl)acetic acid tert-butyl ester; 2-(5-Nitro-2-pyridyl)-2-cyanoacetic acid tert-butyl ester; Acetic acid, 2-cyano-2-(5-nitro-2-pyridinyl)-, 1,1-dimethylethyl ester; tert-Butyl α-cyano-α-(5-nitropyridin-2-yl)acetate; 914223-27-1
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Cyano-2-(5-Nitropyridin-2-Yl)Acetate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider keeping the container under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.