Description

4-Chloro-2-Methyl-Nicotinic Acid is a high-purity, versatile chemical intermediate of significant importance in advanced organic synthesis. Its value lies in its functionalized pyridine core, which serves as a critical building block for constructing complex molecular architectures. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

This specialized nicotinic acid derivative is a key precursor in several high-value industrial and research applications:

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drug candidates targeting the central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where its chlorinated pyridine structure contributes to biological activity.
• Ligand and Catalyst Development: Functions as a precursor for creating complex ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for advanced materials, such as organic semiconductors or metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and tags used in biochemical and diagnostic research.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4-Chloro-2-Methyl-Nicotinic Acid
CAS No.	914219-06-0
Molecular Formula	C7H6ClNO2
Molecular Weight	171.58 g/mol
Synonyms	4-Chloro-2-methylpyridine-3-carboxylic acid; 2-Methyl-4-chloronicotinic acid; 3-Pyridinecarboxylic acid, 4-chloro-2-methyl-; 4-Chloro-2-picolinic acid; 4-Chloro-2-methyl-3-pyridinecarboxylic acid; 2-Methyl-4-chloro-3-pyridinecarboxylic acid; 4-Chloro-2-methylnicotinate
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-2-Methyl-Nicotinic Acid adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality system is designed to meet the rigorous standards required for pharmaceutical and agrochemical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.