Description

1-Isopropyl-3,6-Dimethyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyridine class of heterocyclic compounds. This compound matters as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in drug discovery and development, especially for creating candidates with potential kinase inhibitory or other targeted biological activities.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of complex drug molecules and investigational new drugs.
• Kinase Inhibitor Development: Used in research and development of potential therapeutic agents targeting specific kinase pathways.
• Chemical Research & Development: Employed as a specialized scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in API manufacturing.
• Custom Synthesis: Acts as a starting material for contract research organizations (CROs) and CDMOs performing bespoke synthetic chemistry services.

Basic Information

Product Name	1-Isopropyl-3,6-Dimethyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid
CAS No.	914206-71-6
Molecular Formula	C₁₂H₁₅N₃O₂
Molecular Weight	233.27 g/mol
Synonyms	1-Isopropyl-3,6-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 4-Carboxy-1-isopropyl-3,6-dimethylpyrazolo[3,4-b]pyridine; 1H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 1-(1-methylethyl)-3,6-dimethyl-; 914206-71-6; Pyrazolopyridine-4-carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our 1-Isopropyl-3,6-Dimethyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.