Description

5-Bromopyridine-3-Sulphonyl Chloride Hydrochloride 95 is a high-purity, reactive chemical intermediate primarily used in advanced organic synthesis. This compound is valued for its role as a key building block in the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is essential for chemists and process engineers in fine chemical manufacturing, where it facilitates the introduction of the sulphonyl chloride functional group into pyridine-based scaffolds. The product's consistent quality and reliable reactivity make it a critical component for R&D and scale-up activities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting neurological disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific electronic properties.
• Chemical Biology Probes: Utilized to develop sulfonamide-based probes and inhibitors for studying enzyme function and protein interactions.
• Custom Synthesis and Contract Manufacturing: A key raw material for CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	5-Bromopyridine-3-Sulphonyl Chloride Hydrochloride 95
CAS No.	913836-25-6
Molecular Formula	C5H4BrClNO2S • HCl
Molecular Weight	315.43 g/mol (Free base: 274.51 g/mol)
Synonyms	3-Bromo-5-chlorosulfonylpyridine hydrochloride; 5-Bromo-3-pyridinesulfonyl chloride hydrochloride; 5-Bromopyridine-3-sulfonyl chloride HCl; 3-Pyridinesulfonyl chloride, 5-bromo-, hydrochloride; 913836-25-6; 5-Br-Py-3-SO2Cl • HCl
EINECS	Contact for details

Quality Control

Our 5-Bromopyridine-3-Sulphonyl Chloride Hydrochloride 95 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.