Description

1H-Pyrrolo[2,3-B]Pyridin-4-Ol, 2-(3,4,5-Trimethoxyphenyl)- is a high-purity, advanced pharmaceutical intermediate with the CAS number 913698-77-8. This compound is valued for its complex heterocyclic structure, which serves as a critical building block in modern medicinal chemistry. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in oncology and targeted drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small-molecule drug candidates targeting specific biological pathways.
• Oncology Research: Used in the development of kinase inhibitors and other targeted cancer therapies due to its privileged scaffold.
• Medicinal Chemistry R&D: Serves as a versatile core structure for structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Tool Compound: Utilized in high-throughput screening and biological assay development to study enzyme function and cellular processes.
• Contract Manufacturing (CMO): Supplied to custom synthesis organizations for the production of clinical trial materials and niche APIs.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridin-4-Ol, 2-(3,4,5-Trimethoxyphenyl)-
CAS No.	913698-77-8
Molecular Formula	C16H16N2O4
Molecular Weight	300.31 g/mol
Synonyms	2-(3,4,5-Trimethoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-4-ol; 4-Hydroxy-2-(3,4,5-trimethoxyphenyl)-1H-pyrrolo[2,3-b]pyridine; 913698-77-8; 2-(3,4,5-Trimethoxyphenyl)-4-hydroxy-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridin-4-ol, 2-(3,4,5-trimethoxyphenyl)-; 4-Hydroxy-2-(3,4,5-trimethoxyphenyl)pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridin-4-Ol, 2-(3,4,5-Trimethoxhenyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with exacting research and development standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.