Description

[2-Hydroxy-2-(4-Pyridinyl)Ethyl]-Carbamic Acid 1,1-Dimethylethyl Ester is a high-purity, protected amino alcohol derivative of significant interest in advanced organic synthesis. This compound serves as a critical building block and intermediate for the development of complex pharmaceutical molecules and bioactive compounds. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing pyridine and amino alcohol pharmacophores.
• Protecting Group Chemistry: The tert-butyloxycarbonyl (Boc) group provides a versatile protective strategy for amines during multi-step synthetic sequences.
• Ligand Synthesis: Used in the preparation of chiral and achiral ligands for catalysis, leveraging the pyridine nitrogen and hydroxyl group for metal coordination.
• Peptidomimetic Research: Acts as a scaffold for designing and synthesizing peptide analogs and mimetics in medicinal chemistry programs.
• Agrochemical Development: Serves as a precursor in the creation of novel herbicides, fungicides, or insecticides that utilize its specific heterocyclic structure.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploration of new chemical reactions.

Basic Information

Product Name	[2-Hydroxy-2-(4-Pyridinyl)Ethyl]-Carbamic Acid 1,1-Dimethylethyl Ester
CAS No.	913642-43-0
Molecular Formula	C12H18N2O3
Molecular Weight	238.28 g/mol
Synonyms	tert-Butyl N-[2-hydroxy-2-(pyridin-4-yl)ethyl]carbamate; 4-(2-((tert-Butoxycarbonyl)amino)-1-hydroxyethyl)pyridine; 2-((tert-Butoxycarbonyl)amino)-2-(4-pyridyl)ethanol; Boc-4-Pyridylethanolamine; N-Boc-2-amino-2-(4-pyridyl)ethanol; 1-(4-Pyridyl)-2-((tert-butoxycarbonyl)amino)ethanol; 2-(Boc-amino)-2-(4-pyridyl)ethanol; N-(tert-Butoxycarbonyl)-2-amino-2-(4-pyridinyl)ethanol
EINECS	Contact for details

Quality Control

Our [2-Hydroxy-2-(4-Pyridinyl)Ethyl]-Carbamic Acid 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.