Description

[2-(4-Bromo-Phenyl)-2-Hydroxy-Ethyl]-Carbamic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its unique brominated aromatic and protected carbamate structure. This compound is critical for synthetic chemists requiring a versatile building block for the development of complex active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily utilized in research and development, process chemistry, and commercial manufacturing within the global pharmaceutical and agrochemical sectors.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides, leveraging its bromophenyl moiety.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex molecular architectures via reactions at the hydroxyl or carbamate functional groups.
• Protecting Group Chemistry: The tert-butyloxycarbonyl (Boc) protecting group is instrumental in multi-step peptide and organic syntheses, allowing for selective deprotection.
• Chemical Research: Utilized in methodological studies and the development of new catalytic or asymmetric synthetic routes.

Basic Information

Product Name	[2-(4-Bromo-Phenyl)-2-Hydroxy-Ethyl]-Carbamic Acid tert-Butyl Ester
CAS No.	913181-90-5
Molecular Formula	C₁₃H₁₈BrNO₃
Molecular Weight	316.19 g/mol
Synonyms	tert-Butyl N-[2-(4-bromophenyl)-2-hydroxyethyl]carbamate; 2-(4-Bromophenyl)-2-hydroxyethyl carbamic acid tert-butyl ester; N-Boc-2-amino-1-(4-bromophenyl)ethanol; 1-(4-Bromophenyl)-2-[(tert-butoxycarbonyl)amino]ethanol; Boc-4-Bromo-PEA; Boc-4-Bromophenylethanolamine; (RS)-2-[(tert-Butoxycarbonyl)amino]-2-(4-bromophenyl)ethanol
EINECS	Contact for details

Quality Control

Our [2-(4-Bromo-Phenyl)-2-Hydroxy-Ethyl]-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the highest standards of purity and consistency required for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.