Description

Benzo[D][1,2,3]Triazol-1-Yl-2-(2-(Pyridin-2-Yl)Disulfanyl) Ethyl Carbonate is a specialized heterocyclic compound featuring a benzotriazole core linked via a carbonate ester to a pyridyl disulfide moiety, making it a valuable reagent for advanced organic synthesis and bioconjugation. Its primary value lies in its dual functionality, serving as a photoactivatable protecting group and a cleavable linker for controlled release applications. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries developing prodrugs, polymer conjugates, and stimuli-responsive delivery systems.

Application

• Prodrug Synthesis: Acts as a photo-labile linker for constructing targeted prodrugs that release active pharmaceutical ingredients (APIs) upon light irradiation.
• Bioconjugation & Protein Labeling: Utilized for site-specific modification of peptides, proteins, and antibodies via its reactive disulfide and carbonate groups.
• Polymer Chemistry: Serves as a functional monomer or cross-linking agent for creating smart polymers with light-cleavable or redox-responsive properties.
• Controlled Release Systems: Incorporated into nanoparticles, hydrogels, and micelles to enable triggered payload release in response to specific biological or external stimuli.
• Chemical Biology Tools: Used in the development of probes and assays to study enzyme activity, cellular uptake, and intracellular trafficking.
• Agrochemical Research: Applied in the design of novel, environmentally responsive pesticide and herbicide delivery formulations.
• Surface Functionalization: Enables the covalent attachment of biomolecules to surfaces for biosensor and diagnostic device development.
• Linker for Solid-Phase Synthesis: Provides a cleavable anchor in multi-step organic synthesis on solid supports.

Basic Information

Item	Details
Product Name	Benzo[D][1,2,3]Triazol-1-Yl-2-(2-(Pyridin-2-Yl)Disulfanyl) Ethyl Carbonate
CAS No.	913168-10-2
Molecular Formula	C16H13N5O3S2
Molecular Weight	395.43 g/mol
Synonyms	1-(2-((Pyridin-2-yldisulfanyl)ethoxy)carbonyloxy)-1H-benzotriazole; 2-(Pyridin-2-yldisulfanyl)ethyl (1H-Benzotriazol-1-yl) Carbonate; Benzotriazol-1-yl 2-(2-pyridinyldithio)ethyl carbonate; Bt-PySS Carbonate; Photo-cleavable Pyridyl Disulfide Carbonate; PySS-Bt Carbonate; 1H-Benzotriazol-1-yl 2-(2-pyridinyldithio)ethyl carbonate; 913168-10-2
EINECS	Contact for details

Quality Control

Our Benzo[D][1,2,3]Triazol-1-Yl-2-(2-(Pyridin-2-Yl)Disulfanyl) Ethyl Carbonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and specific tests for residual solvents and moisture content. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C to -10°C under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. This compound is moisture-sensitive and should be handled in a dry environment. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with reference structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.