Description

6-(Difluoromethyl)Pyridine-3-Carboxylic Acid is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the difluoromethyl group adjacent to the carboxylic acid functionality, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluoromethyl group can enhance metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials that require specific fluorinated aromatic components.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	6-(Difluoromethyl)Pyridine-3-Carboxylic Acid
CAS No.	913091-98-2
Molecular Formula	C7H5F2NO2
Molecular Weight	173.12 g/mol
Synonyms	3-Pyridinecarboxylic acid, 6-(difluoromethyl)-; 6-Difluoromethylnicotinic Acid; 2-Difluoromethyl-5-pyridinecarboxylic Acid; 5-Carboxy-2-difluoromethylpyridine; 6-(Difluoromethyl)nicotinic Acid; Difluoromethyl Pyridine Carboxylic Acid; DFMPA
EINECS	Contact for details

Quality Control

Our 6-(Difluoromethyl)Pyridine-3-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.