Description

4-Chloro-2-(3,4,5-Trimethoxyphenyl)-1H-Pyrrolo[2,3-B]Pyridine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel, biologically active molecules, particularly in oncology and other therapeutic areas. It is primarily sought by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A critical precursor in the research and development of new drug candidates, especially kinase inhibitors and other targeted therapies.
• Organic Synthesis Building Block: Used in complex multi-step syntheses to construct novel molecular scaffolds for biological screening.
• Medicinal Chemistry Research: Serves as a core structure for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for fundamental studies in heterocyclic chemistry and bioorganic chemistry.

Basic Information

Product Name	4-Chloro-2-(3,4,5-Trimethoxyphenyl)-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	913083-71-3
Molecular Formula	C18H17ClN2O3
Molecular Weight	344.79 g/mol
Synonyms	4-Chloro-2-(3,4,5-trimethoxyphenyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-2-(3,4,5-trimethoxyphenyl)-; 913083-71-3; 4-Chloro-2-(3,4,5-trimethoxyphenyl)-7-azaindole; 2-(3,4,5-Trimethoxyphenyl)-4-chloro-1H-pyrrolo[2,3-b]pyridine; 4-Chloro-2-(3,4,5-trimethoxyphenyl)-7H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(3,4,5-Trimethoxyphenyl)-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.