Description

2-(2-Nitro-Pyridin-3-Yl)Oxymethyl-2,5-Dihydro-Pyrrole-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for enabling sophisticated synthetic routes in medicinal chemistry, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the synthesis of complex molecules for therapeutic applications.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with improved efficacy and safety profiles.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the global pharmaceutical industry.
• Academic Research: Employed in university and institutional labs for studying novel heterocyclic reactions and developing new synthetic methodologies.

Basic Information

Product Name	2-(2-Nitro-Pyridin-3-Yl)Oxymethyl-2,5-Dihydro-Pyrrole-1-Carboxylic Acid tert-Butyl Ester
CAS No.	912843-70-0
Molecular Formula	C15H19N3O5
Molecular Weight	321.33 g/mol
Synonyms	tert-Butyl 2-(((2-nitropyridin-3-yl)oxy)methyl)-2,5-dihydro-1H-pyrrole-1-carboxylate; 1-(1,1-Dimethylethyl) 2-[[(2-nitro-3-pyridinyl)oxy]methyl]-2,5-dihydro-1H-pyrrole-1,2-dicarboxylate; 2,5-Dihydro-1H-pyrrole-1,2-dicarboxylic acid, 2-[[(2-nitro-3-pyridinyl)oxy]methyl]-, 1-(1,1-dimethylethyl) ester; 912843-70-0; BRN 19105085
EINECS	Contact for details

Quality Control

Our 2-(2-Nitro-Pyridin-3-Yl)Oxymethyl-2,5-Dihydro-Pyrrole-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.